Stem_Cell_HealthStem_Cells

Amnionic Fluid-Another Source For Stem Cells

Fetal stem cells have been another source of controversy through the years.  Some people disagree with using a fetus for stem cell research.  Several factors are involved in the controversy.  Aborted fetuses, via abortion, were used at one time for a source of fetal stem cells.  Unplanned miscarriages are another source.  These avenues evokes many emotions in people no matter what the source of fetal stem cells are.  Another avenue for fetal stem cells has been discovered in the amnionic fluid surrounding the fetus growing in the womb. A routine and generally safe medical procedure, known as amniocentesis, is the therapy used to extract a small amount of the amnionic fluid in which to process the fetal stem cells.

Ming-Song Tsai, Shiaw-Min Hwang, Yieh-Loong Tsai, Fu-Chou Cheng, Jia-Ling Lee, and Yu-Jen Chang in Taiwan wrote a research paper entitled, Clonal Amniotic Fluid-Derived Stem Cells Express Characteristics of Both Mesenchymal and Neural Stem Cellsno access, describing the merits of amnionic fluid in stem cell use.

The summary is as follows:

“Recent evidence has shown that amniotic fluid may be a novel source of fetal stem cells for therapeutic transplantation. We previously developed a two-stage culture protocol to isolate a population of amniotic fluid-derived mesenchymal stem cells (AFMSCs) from second-trimester amniocentesis. AFMSCs maintain the capacity to differentiate into multiple mesenchymal lineages and neuron-like cells. It is unclear whether amniotic fluid contains heterogeneous populations of stem cells or a subpopulation of primitive stem cells that are similar to marrow stromal cells showing the behavior of neural progenitors. In this study, we showed a subpopulation of amniotic fluid-derived stem cells (AF-SCs) at the single-cell level by limiting dilution. We found that NANOG- and POU5F1 (also known as OCT4)-expressing cells still existed in the expanded single cell-derived AF-SCs. Aside from the common mesenchymal characteristics, these clonal AF-SCs also exhibit multiple phenotypes of neural-derived cells such as NES, TUBB3, NEFH, NEUNA60, GALC, and GFAP expressions both before and after neural induction. Most importantly, HPLC analysis showed the evidence of dopamine release in the extract of dopaminergic-induced clonal AF-SCs. The results of this study suggest that besides being an easily accessible and expandable source of fetal stem cells, amniotic fluid will provide a promising source of neural progenitor cells that may be used in future cellular therapies for neurodegenerative diseases and nervous system injuries.”

This is very promising news for neuronal impairment in people suffering from diseases and injuries.

Stem Cells Work For Stomach Regeneration

Many middle aged and elderly adults understand the role of the gut in health.  The release of digestive enzymes and hydrochloric acid in the stomach are very important to digestion of foods and affect the vibrancy of life.  The advances in stem cell research show that stem cells can cause midgut or mid – stomach … Continue reading

Stem Cell Research Pros

Stem cell research pros has shown us that stem cells are special cells which, when given specialized signal, can become any part of the body needed for regeneration.  The body may need muscle cells, blood cells, skin cells, organ cells, nervous system cells, etc.  The stem cells will go in and sweep up the cells … Continue reading

Stem Cell Research Pros and Cons

Like everything in life, stem cell research is not exempt from having both pros and cons. Let’s look at some aspects about stem cell research pros and cons that are of particular interest and usefulness to anyone interested in the subject of stem cells. Stem cell research has been shrouded in controversy as people fight … Continue reading

Breast Cell Found To Have Stem Cell Like Capabilities Of Producing Cancer

Stem cell – like cells can be turned cancerous in breast tissue.  Researchers from Michigan State University characterized two types of breast epithelial cell types, with one type possessing the ability to become mutinous under certain conditions because these particular cells exhibit stem cell-like characteristics that can turn into breast cancer. The epithelial cells make … Continue reading

Culturing Stem Cells – New Advances Found

Few researchers think about the container used to culture and grow stem cells.  What researchers found is that flasks coated in agarose gel produced more stem cells and furthermore, the stem cells remained multipotent!  Agarose gel is an electrical conductor gel made from a seaweed. These researchers from China, Xue-Sheng Zheng, Xiao-Feng Yang, Wei-Guo Liu, Gang … Continue reading

Stem Cells Offer New Hope For Parkinson’s Disease Sufferers

Stem Cells show promise in brain regeneration for Parkinson’s disease sufferers. Parkinson’s disease is a sadly debilitating disease affecting over 50,000 people in the United States with approximately 10 million people suffering worldwide.  Parkinson’s symptoms can begin before the age of 40, making this disease widespread. Zhiqing Zhang, Xiaofang Wang, Suping Wang in China found … Continue reading

Stem Cells From Sperm Offers New Treatment For Male Infertility

Most people only hear of embryonic, fetal, cord blood stem cells, or bone marrow stem cells.  Stem cells are actually produced throughout the body.  One interesting place that stem cells are very prolific, and makes the most sense concerning the beginning of life, is the male testes (i.e. sperm stem cells). Here is a medical … Continue reading

Which Source of Stem Cells is Best?

Many people wonder what the best source of mesenchymal stem cells is: Bone marrow? Umbilical cord blood? Adipose or fat? Let’s look at the findings of Susan Kern, et al, from the Institute of Transfusion Medicine and Immunology, German Red Cross Blood Service of Baden-Württemberg–Hessen, Mannheim, Germany. In a paper titled: “Comparative Analysis of Mesenchymal … Continue reading

How to Handle Potential Infections in Stem Cell Research

Anytime you are dealing with human or animal tissue, there is the danger of infection or the spreading of disease. In Spain they have been working on this issue for years and there is a paper by Fernando Cobo of the Stem Cell Bank of Andalucía in which he addresses this issue. Here is a … Continue reading